Exosome Cica Ampoule
Ingredients
Centella Asiatica Leaf Water, Water(Aqua), Glycerin, Butylene Glycol, Methylpropanediol, Glycereth-26, Niacinamide, 1, 2-Hexanediol, Betaine, Carbomer, Tromethamine, Glycereth-25 PCA Isostearate, Ethylhexylglycerin, Dipotassium Glycyrrhizate, Allantoin, Glyceryl Acrylate/Acrylic Acid Copolymer, Panthenol, Gardenia Florida Fruit Extract, Coptis Japonica Extract, Centella Asiatica Root Extract, Centella Asiatica Leaf Extract, Centella Asiatica Extract, Hydrogenated Lecithin, Melaleuca Alternifolia (Tea Tree) Leaf Water, Propanediol, Madecassoside, Glycyrrhiza Uralensis (Licorice) Extract, Ectoin, Dipropylene Glycol, Centella Asiatica Leaf Vesicles, Caprylic/Capric Triglyceride, Biosaccharide Gum-1, Pentylene Glycol, Melaleuca Alternifolia (Tea Tree) Extract, Sodium Hyaluronate, Vegetable Amino Acids, Saccharide Isomerate, Lactobacillus Ferment Filtrate, Hydrolyzed Vegetable Protein, Hyaluronic Acid, Houttuynia Cordata Extract, Asiaticoside, Madecassic Acid, Asiatic Acid
This is the serum counterpart to Medicube's calming toner I've reviewed previously. Like the toner, it’s meant to be an incredibly soothing product.
Texture-wise, this serum is gooey. Like, genuinely jelly-textured — green, cooling, and strangely satisfying to smear across your face. It feels refreshing on application and settles into the skin nicely without stickiness. Just like the toner, this is a delight to use on overheated skin. And with this serum, I can actually see my redness subside with regular use.
The formula reads like a Centella greatest hits compilation — Centella water, Centella extract, Centella root, leaf, madecassoside, asiaticoside, asiatic acid, madecassic acid — basically the whole plant thrown in, processed in every conceivable way. There’s also niacinamide, dipotassium glycyrrhizate, allantoin, and panthenol, all solid choices for soothing and barrier support.
And yes — just like in the toner — Centella Asiatica Leaf Vesicles show up again. As noted before, this isn't a verified exosome, no matter how biotech-adjacent it sounds. These vesicles are not proven to deliver signals or “talk” to skin cells like real exosomes do — they’re more likely just Centella delivery systems in fancier packaging. You also get Lactobacillus Ferment Filtrate, another ingredient sometimes vaguely associated with exosome-like effects, though in reality, it’s just fermented broth, not a purified vesicle with cell-to-cell communication potential.
Bottom line? This is a well-formulated soothing serum, heavy on Centella, with enough modern flair to catch attention. It really delivers on what it promises. Just don’t let the “exosome” talk convince you it’s doing something it hasn’t proven it can.


