Summary: A blended chemical peel composed of salicylic acid, lactic acid, and resorcinol in an ethanol base.
Jessner’s Solution is a standardized formulation used in superficial to medium-depth chemical peels. It typically contains 14% salicylic acid (a BHA), 14% lactic acid (an AHA), and 14% resorcinol, all dissolved in 95% ethanol. Each component plays a distinct role: salicylic acid penetrates into pores and aids exfoliation; lactic acid loosens dead skin cells on the surface; and resorcinol enhances cell turnover and has antiseptic properties. The ethanol base facilitates uniform application and enhances skin penetration.
Jessner’s Solution is often used to treat conditions such as acne, hyperpigmentation, and photoaging. Modified versions may adjust or omit resorcinol due to sensitivity concerns.
References: Pinto, J.M.N., Delorenze, L.M., Vasques, W., & Issa, M.C. (2016). Jessner’s Peel. In M. Issa & B. Tamura (Eds.), Chemical and Physical Peelings. Clinical Approaches and Procedures in Cosmetic Dermatology. Springer, Cham. Jessner’s Peel | SpringerLink